Veterinary drug "Advocate" for dogs: dosage, instructions

Advocate drops (original name Advocate) for dogs are used as a means of preventing and treating our beloved pets with entomosis, nematodosis, sarcoptoidosis, otodecosis and demodicosis. Successful use of the drug has been noted for allergic dermatitis and dirofilariasis. Advocate drops for dogs, instructions for which are included with each package, perfectly destroy fleas on cats and dogs, which our pets often bring back from walks, so they are recommended not only for dogs, but also for cats. The drug is produced by Bayer (Germany).

Pharmacology and composition

Advocate drops for dogs are produced by the world-famous German company Bayer HealthCare AG. Veterinary products from this company are widely known in the pharmacological market and have been successfully used for years to treat and prevent diseases in animals.

The drug is a complex antiparasitic agent. It acts through the synthesis of 2 substances:

• imidacloprid: insecticide, causes the death of ticks and fleas;
• moxidectin: acts against nematodes (worms).

Imidacloprid spreads throughout the dog's skin and coat. It is released along with sebaceous secretions, penetrates the bodies of insects during bites, causing their paralysis and subsequent death. Moxidectin enters the systemic bloodstream, tissues and organs, leading to muscle innervation of nematodes and, as a result, death. Both substances protect against parasites for up to 1 month.

Moxidectin is similar in action to ivermectin. But, unlike it, it is not toxic to collies and similar breeds.

The effectiveness of “Advocate” drops

As soon as the drug enters the skin of a pet, it is rapidly distributed throughout the epidermis and fur. The active substance protects cats and dogs for a long time, providing an insectoacaricidal effect.

“Advocate” drops, unlike other products, penetrate through the skin into the internal organs, which enhances their effect

Unlike imidacloprid, moxidectin does not work on the surface, but inside the body. It enters the systemic bloodstream through the skin, from where it begins to be distributed to tissues and organs. The maximum dose of the active substance of the drug is recorded on days 4-9 after treatment. Complete elimination of moxidectin occurs after four weeks.

Attention! The active substance of the drug practically does not reduce its effectiveness even after the animal’s fur and epidermis are wet. But veterinarians do not recommend immediately letting your pet near water or bathing him with shampoo after applying drops to the withers. In the future, until the course of therapy is completed, the use of soap solutions should be moderate and only when really necessary.

Correct way to apply drops

Properties and pharmacodynamics

Thanks to its balanced composition, Advocate has a pronounced insecticidal and acaricidal effect. Refers to universal, combined medications with prolonged action.

Imidacloprid is a substance belonging to the group of chloronicotinyl insecticides. The mechanism of action is based on disruption of innervation, transmission of nerve impulses of ectoparasites, as well as interaction with acetylcholine receptors of arthropod blood-sucking insects, which leads to their death.

Advocate for dogs is available in pipettes of various sizes.

Moxidectin is a semi-synthetic compound from the milbemycin group. It is quickly adsorbed through the skin, penetrates the bloodstream, is evenly distributed in the body, and provides a prolonged effect. It has a stimulating effect on the release of gamma-aminobutyric acid, which, by binding to postsynaptic receptors of ecto- and endoparasites, provokes disruption of muscle innervation, which leads to instant paralysis and death of fleas, ticks, and nematodes.

The insecticidal effect after a single treatment of dogs lasts for four to six weeks, and the acaricidal effect lasts for 28-35 days.

Composition and release form

The drug “Advocate” for dogs (the original name is Advocate) is produced by the German pharmacological company Bayer, which has managed to earn trust among consumers all over the world. The antiparasitic medicine is available in liquid form, which is packaged in polypropylene pipettes. The volume can be different - from 0.4 to 4.0 ml, which simplifies the selection of the drug taking into account the dosage. There are usually three pipettes in one package, but many veterinary pharmacies sell them individually. The drug is intended for external use only, as it contains toxic substances.

“Advocate” prevents infection by ticks, fleas, nematodes and other ectoparasites. It has a wide spectrum of action, so it is quite popular among dog breeders. It contains two active ingredients:

1. Imidacloprid acts on the nervous system through insect receptors, stopping the transmission of nerve impulses. As a result, the parasites die pretty soon.
2. Moxylectin causes muscle dysfunction and paralysis, which inevitably leads to the death of arthropods.

In addition, the composition includes propylene carbonate, benzyl alcohol and other auxiliary components.

Indications for use

Drops on the withers Advocate are a combined broad-spectrum antiparasitic agent. It is effective against:

• mites – demodectic, sarcoptoid;
• fleas;
• lice;
• lice eaters;
• adult and larval forms of nematodes - roundworms (toxacara, hookworm, uncinaria) and whipworms (trichocephalosis);
• dirofilaria larvae - a type of worm that affects organs: heart, lungs, eyes, etc.

The medicine is not effective against ixodid ticks and adult heartworms. Therefore, if the dog is already affected by these types of parasites, the drug is combined with other drugs.

An antiparasitic agent is used for:

• prevention of infection with helminths and ectoparasites;
• prevention of dirofilariasis;
• destruction of fleas, lice, lice, ticks, worms;
• complex therapy of otitis and allergic dermatitis caused by insects;
• treatment of sarcoptic mange, demodicosis.

Pharmacology

Imidacloprid accumulates in the sebaceous glands, hair follicles, skin epidermis, and hairs. The poisonous substance comes into contact with the arthropod and causes paralysis. When a fly, mosquito or ixodid tick comes into contact with a pet's fur, they die or refuse to attack.

Moxidectin penetrates the skin and is absorbed into the blood. Along the way, the active component blocks the nerve impulses of itch mites and helminths. Both components have a toxic effect against parasites for a month.

Lawyer for dogs - description of the drug

The drug has an antiparasitic effect and is capable of destroying lice, ticks, worms, fleas, lice eaters and other parasites. Lawyer is prescribed for animals suffering from diseases such as nematodosis, demodicosis, sarcopticosis and entomosis. It is also used as a preventive measure for certain types of diseases in dogs.

Active substances

Imidacloprid and moxidectin. Both substances stimulate the death of insects on the animal’s body by influencing nerve impulses and postsynaptic receptors of parasites.

Operating principle

Parasites are mostly affected by substances such as moxidectin and imidacloprid, which are activators of the following processes:

1. Stimulation of a number of channels that exhibit the greatest degree of sensitivity to chlorine and glutamate, which ultimately leads to an increased influx of chloride ions.
2. Influencing the central nervous system of parasites, which causes paralysis in them, subsequently leading to death, while there is no effect on warm-blooded creatures.
3. Activation of a number of receptors in various types of parasites that have increased sensitivity to the nicotine group of substances.

Instructions for use and dosage

Advocate drops (spot-on) are produced in various packaging according to the weight of the animal. The dosage is calculated based on their recommended norms - 0.1 ml of the drug per 1 kg of animal weight, which corresponds to 10 mg of imidacloprid and 2.5 mg of moxidectin per 1 kg.

If the pet's weight exceeds 40 kg, combine two pipettes whose volume best matches the animal's weight. For example, for a dog weighing 43 kg, a combination of 4 ml and 0.4 ml drugs is suitable. And for a dog weighing 46 kg, 4 ml and 1 ml are combined.

Applying drops is no different from using similar products. Follow the step-by-step instructions:

• the animal is fixed - large dogs are held on the floor, medium and small dogs are lifted onto the table;
• open the pipette - remove the protective cap and pierce the tip of the tube with its reverse side;
• move the fur apart - the drug must get on the skin, otherwise it will flow down the fur coat and will not penetrate the body;
• examine the skin - it must be clean, dry, without damage or redness, otherwise the drops cannot be used;
• apply the medicine - drop it into 3-4 points that are inaccessible for licking (from the withers to the lower back), it is better to apply immediately behind the ears in front of the scruff of the neck.

The frequency of use depends on the clinical case and varies from 28 to 64 days. On average, the drug for dogs is recommended to be used once a month during the parasite activity season - from early spring to late autumn.

Features of use and prevention

It is important to protect not only your pet, but also yourself, since “Advocate” drops, if the recommendations for use are not followed, can cause poisoning, including in humans.

1. Do not apply the drug in places close to food. The best use is in an open space or room with good ventilation.
2. Drinking and smoking are prohibited during the procedure.
3. Handling a sick animal is carried out only with gloves, after which you should still wash your hands well with plenty of soap.
4. If the active substance gets on the mucous membrane, you should immediately wash it off with plenty of water.
5. If drops get inside, you need to consult a doctor for possible gastric lavage.

Careless use of the medication can lead to poisoning for both the pet and the owner.

Video - Application and effect of the drug

Precautions and storage rules

Do not forget that the drug is toxic. Following precautions will make it safe to use:

1. Before using “Lawyer” for dogs, please read the instructions. Do not exceed the indicated doses.
2. Do not drink or eat during treatment. In addition, smoking is not allowed.
3. Upon completion of the procedure, wash your hands under running water using soap. If you are sensitive, be sure to wear protective gloves.
4. If the medicine enters the body or mucous membranes, or if an allergy occurs, consult a doctor.
5. After treatment, do not pet the dog for 3-4 days. Do not allow children to play with animals.
6. The medicine should be stored away from feed and food, preventing contact with sunlight, and the temperature should be between 0 and 30°C
7. Prevent access to the drug by animals and children.
8. Medicine containers must be disposed of with household waste. Cannot be used for other purposes.
9. Store only in original packaging.
10. Cannot be used after expiration date.

Contraindications and side effects

Lawyer is a safe remedy. But in case of individual intolerance, it causes signs of allergy - skin hyperemia and itching. In this case, the drug is washed off with a large amount of water, and the animal is given an antihistamine - Suprastin, Tavegil, etc.

Spot-on is prohibited for the following animals:

• kittens up to 7 weeks;
• pregnant and lactating bitches;
• sick and weakened pets;
• dogs weighing less than 1 kg.

In case of urgent need, these animals are treated under the supervision of a veterinarian.

Side effects

Advocate may cause the following side effects:

• itching;
• redness of the skin;
• various allergic reactions.

Adverse reactions are usually rare. If redness and itching appear, you can leave everything as it is - in a couple of days the symptoms will go away on their own. But if the dog has an allergic reaction, the drug must be immediately washed off with soapy water, and the fur must be thoroughly rinsed with plenty of water. After which the animal must be given an antihistamine, according to the instructions attached to it.

You should not use Advocate with any other antiparasitic agents, as this may increase toxicity.

Possible side effects

Even when the permissible doses are observed and used in accordance with the instructions, side effects sometimes occur that are associated with the individual characteristics of the pet.

They may include the following:

1. Digestive disorders, loss of appetite and vomiting.
2. Itching occurs.
3. Dilatation of capillaries, which causes redness of the skin in different places.
4. Wool contamination.

Advantages and disadvantages

Advocate drops on the withers are one of the best antiparasitic remedies. It has many advantages compared to other drugs:

• complex action - one pipette kills ectoparasites and worms, which frees the animal owner from purchasing and feeding deworming tablets;
• safety;
• side effects are minor, occur rarely and go away on their own;
• allowed for use by puppies from 7 weeks;
• an abundance of dosages for dogs of different sizes;
• collies and similar breeds can be used;
• convenient use.

However, the drug also has disadvantages:

Owner reviews

YuliaYa1977: “For the first time we took these drops. The dog did not struggle during treatment and behaved calmly. Overall, she tolerated the drug well - no signs of intoxication. Only the wool smells a little, but after other products the smell was stronger.”

KseniaZH: “Six months ago my pug got sick. He was still a puppy then and didn’t weigh even 4 kg. At first a small pimple appeared on my forehead, which then became covered with skin. The vet said it was a subcutaneous mite and appointed a lawyer. He said to drip for 4 months in a row every 30 days. After the second use, the crusts disappeared, and after the 4th time everything disappeared as if by hand. The price is steep, but I ordered at my own risk on the Internet: it turned out to be almost 2 times cheaper and they sent the original medicine, although I was afraid of a fake.”

Doglover27: “The drops saved us! My dog ​​was itching endlessly. I thought it was fleas, but nothing helped. Then I suffered from a food allergy, changed my diet, and also without results. We went to the vet and he said it was itch mites. These small parasites are not visible, so they could not determine what the dog was sick with. After two applications, the animal stopped itching and suffered from itching.”

Advantages and disadvantages

Many veterinarians recommend the “Advocate” product, since it has many positive aspects.

Its main advantages include:

However, despite so many positive aspects, “Lawyer” also has certain disadvantages, they are as follows:

1. Possibility of side effects.
2. The odor is too strong and unpleasant, which persists for a day after treatment.

Cost and storage conditions

The medication must be stored in room conditions at a temperature not exceeding +30 degrees. It is important to avoid direct sunlight on the packaging. The shelf life of Advocate drops is 3 years. The average price of “Advocate” drops depends on the volume of the pipette and can range from 700 to 1500 rubles.

The drops require careful adherence to the instructions for use so that the cat or dog does not develop undesirable consequences for their health. Let us briefly highlight the most basic of them.

Precautionary rules

When using, you must carefully read the instructions and reviews of the “Lawyer”. This will avoid many mistakes and restore lost health to your pet and protect it in the future.

Indications and contraindications

Indications for the use of the drip drug “Advocate” are the following cases:

1. The need for preventive treatment of a cat or dog against parasites such as lice, fleas or ticks.
2. Treatment of the consequences of subcutaneous mite infestation.
3. Treatment of ear scabies.
4. Treatment of infectious diseases caused by acariform mites.
5. Treatment of diseases caused by different types of insects.
6. Treatment of diseases of the digestive system caused by roundworms.
7. Treatment of difilariasis.

Before you start using this product, you should familiarize yourself with the list of contraindications for its use, these include :

1. The weight of the animal is less than a kilogram.
2. Less than seven weeks old for puppies and less than nine weeks old for kittens.
3. The presence of various diseases that weaken the body, the treatment of which is not directed by the Advocate.
4. Pregnancy and lactation period. In some cases, the use of the “Lawyer” is acceptable and justified, but is carried out only after consultation and obtaining appropriate permission from the veterinarian.
5. Concurrent use of other pharmacological agents, which contain different forms of macrocyclic lactones.

Analogues of the drug

There are few analogs of the Lawyer. It is rare that any veterinary drug manufacturer combines substances against ectoparasites and helminths in one product. Usually, drops for fleas and ticks are produced separately, and tablets for worms are produced separately.

Therefore, funds like the Lawyer can be counted on one hand.

Analogues are better:

Analogues are worse:

Reviews about the use of “Advocate” drops

The majority of consumers who used Advocate drops to treat and protect their pets were satisfied with the course they completed. Cats and dogs, when the active ingredient is applied correctly, rarely show side effects, with the exception of cases of hypersensitivity to the active substance.

Many owners noted the fast and effective operation of the drops

Drops were used not only on animals living in an apartment or city, but also on cats and dogs living in rural areas with a large number of insects and parasites. The medication successfully protected the pet from flies and their larvae, repelled ticks and blood-sucking mosquitoes.

Advocate drops also helped pets living in yards and often forced to come into contact with parasites

When eliminating skin disorders, drops were used both as a separate remedy and as a combination with other medications. They showed an equally good therapeutic effect in two regimens, but were more often used as a separate agent in the initial stages of the disease. According to reviews of those who used Advocate drops on dogs and cats, the first results were noticeable after just a couple of applications.

In some cases, one or two procedures are enough for the pet’s condition to improve.

To eliminate flea and tick attacks, a single treatment is sufficient, while pet owners confirm the long-term effect of the active substance, provided that the dose is selected correctly. Allergic attacks occur in less than 1-2% of cases. Severe anaphylactic reactions are extremely rare and are usually associated with previously unknown contraindications for treating skin and fur.

An allergic reaction to drops is extremely rare.

What to pay attention to

Advocate drops should not be combined with medications containing macrocyclic lactones. Do not apply multiple antiparasitic agents at the same time. Make sure that the dog does not lick the drug or chew the pipette. If this happens, take her to the veterinary clinic immediately.

Advocate is a moderately dangerous drug. Therefore, a person must take precautions when working with it. Do not eat, drink or smoke while opening the pipette. After the procedure, wash your hands with soap. Dispose of any remaining packaging immediately.

Answers to frequently asked questions

When can you bathe your dog?

It is advisable not to wash your dog with shampoo for 4 days before and after treatment. Detergents break down the lipid layer, which reduces the effectiveness of the flea and tick product. Although bathing does not affect the anthelmintic effect of the drug.

If the dog got caught in the rain, ran through puddles, or jumped into a pond for a couple of minutes, it’s okay. The effect of the drops will continue.

The dog weighs less than the minimum dosage - up to 4 kg. How to proceed?

For animals weighing over 1 kg, the entire 0.4 ml pipette can be used under the supervision of a veterinarian. As a rule, the medicine does not cause side effects. If the dog weighs less, a lawyer cannot be used.

I have two dogs weighing about 20 kg. Is it possible for them to take one pipette for giant breeds (weighing up to 40 kg) and divide it equally?

You cannot divide the pipette - this makes it impossible to calculate the correct dosage. For each dog, a release form is purchased that corresponds to its weight.

Does Lawyer help against ixodid ticks?

The drug is not effective against ixodid ticks. To destroy this type of parasite or prevent infection by it, Advantix is ​​first used. And after 2-7 days they use Advocate.

Can it be used in conjunction with other antiparasitic agents?

Drops cannot be used along with similar drugs. The exception is Advantix and the Foresto collar. They contain different active ingredients and together protect against all types of parasites.

Reviews from dog breeders

Dog owners note the high effectiveness of the drug Advocate. Marina, owner of a Labrador, Moscow. I was always skeptical about drops on the withers and preferred to use anti-flea shampoos. But when I got a large dog, I realized that washing with shampoo was not the answer. As a result, I bought these drops before going to the country. We were pleased with the result; we didn’t bring any fleas! True, I applied the drug generously, the dog is still large. I will continue to use them, the drops really work.

Anna, St. Petersburg. I tried different drugs for parasites, but most of the tablets simply made the dog sick. The effect is zero. On the advice of the veterinarian, I bought these drops. It’s convenient that you can buy just one pipette at the pharmacy, everything is calculated by weight. The dog (I have a teenage Cane Corso) tolerated the procedure calmly, there were no problems with his fur, and no nausea either. This is the second time I have purchased this product and I am satisfied.

Andrey, Tver. My first dog already suffered from demodicosis, so I monitored the health of the second one especially closely. I chose Lawyer after consulting with a veterinarian. A little expensive, of course, but the result is good. It's nice to know your pet is safe. Now both of my pit bulls are treated 4 times a year. There are no side effects, I liked that the drops are suitable even for puppies, which means they are safe.

Description

And one more good news. To buy such a thoughtful remedy for worms, fleas and ticks, you don’t even have to leave your home. Fill out an application on our website or contact the manager, and in the near future we will deliver Advocate drops to any location in Russia. And for those who live in Moscow or the Moscow region, we suggest using the services of a courier service.

You can buy Lawyer Drops on the Withers against Ticks, Fleas and Worms for Dogs at a price starting from 394 rubles! Composition, photos, reviews about Lawyer Drops on the Withers against Ticks, Fleas and Worms for Dogs, delivery of goods throughout Moscow and all of Russia, we accept orders seven days a week!

Excipients: propylene carbonate, benzyl alcohol, butylated hydroxytoluene.

Advocate belongs to the group of moderately toxic medications (hazard class 3). If the recommended dosage specified in the annotation is followed, it does not provoke side effects in dogs. Does not have a carcinogenic, teratogenic, local irritating or sensitizing effect. The active components of the drops do not penetrate the blood-brain barrier of warm-blooded animals.

Important! Advocate can be used for dogs of all breeds, different age groups, including ivermectin-sensitive breeds (collie, sheltie).

As indicated in the instructions, the veterinary drug must be stored at a temperature of 0 to 25 degrees, in dry, dark places in the original packaging. From the date of release, the shelf life is three years.

Content

1. Advocate for dogs: pharmacological effects 2. Dosage and methods of administration 3. Cost of Advocate drops in pharmacies and clinics 4. Contraindications and side effects of Advocate for dogs 5. Reviews

An antiparasitic veterinary drug is necessary to combat ticks, fleas and internal parasites that live in the pet's gastrointestinal tract. Drops against worms and fleas are developed using German equipment by the world famous company Bayer. Their cost is quite acceptable for owners of all breeds of dogs and cats. The drug is available only in the form of a solution; there are no tablets or suspensions.

Most often, the indications for prescribing a medical product are diseases such as: demodicosis, the presence of lice, detection of lice, a positive test for the presence of cestodes, nematodes, trematodes in the body, for scabies of the eyes, nose, ears. Before prescribing a pharmaceutical drug for parasites for dogs, it is recommended to undergo a comprehensive examination at a veterinarian's office. Preventive visits to the doctor are the key to your pet’s excellent health and well-being. Before using the remedy for helminths and lice, you must carefully study the instructions in order to avoid an overdose.

A dog advocate has a relatively high cost. Why the price is justified:

• The drug belongs to the fourth safety class, which guarantees no accumulation in the dog’s liver tissue, and also prevents harmful effects on the pet’s immune system.
• Anti-parasite drops have been fully tested and meet international quality and safety standards.
• They are sold in special packaging with a dispenser, which makes it convenient to measure the smallest doses.
• The medicine is used sparingly, since the effect of the drug lasts up to 4 weeks.
• The pharmaceutical product does not lose its activity even if, 2-3 weeks after application, the dog was exposed to rain or took a home bath.
• The shelf life of Advocate drops is 3 years, but all rules for storing the substance must be followed.

A combined drug with a wide spectrum of action will allow you to avoid wearing special collars, routine deworming, and unnecessary stress for your beloved pet.

Precautions when applying the drug

Despite the fact that Lawyer is safe for human health, neglect the simplest precautions

not worth it:

• The person handling the animal is recommended to wear gloves.
• If the product gets on mucous membranes (eyes, mouth, etc.), you should immediately rinse these areas with water.
• The processing process should be carried out in the fresh air or in a well-ventilated area, away from food, children's toys and personal hygiene products.
• If a person is the owner of several animals, then all pets need to be treated with flea medication on the same day.

Reviews about the drug

Below are the opinions of people about Advocate drops who have already used them to treat their pets:

1. Anna: “The veterinarian recommended using antiparasitic agents for prevention. I tried to mix tablets into food - the cat flatly refused to eat it. Even the product, whose instructions stated that it tasted and smelled attractive to animals, was ignored. I decided to try “Advocate” in the form of drops; in the end, it only had two drawbacks: high cost and an unpleasant odor, but this drug is very easy to use.”
2. Vladimir: “It was necessary to treat a dog that had parasites, as well as cats for prevention, since they could also become infected. I spent a long time choosing a product, read a lot of reviews and recommendations, and finally settled on “Lawyer.” The choice was influenced by the fact that it is produced by Bayer, and this company has managed to establish itself well and is well known. In addition, the positive point was the fact that the drops can be used for both cats and dogs, and this saved me from the need to purchase several medications. As a result: all parasites were removed from the dog, no intoxication or any side effects were observed; no other animals became infected. The high price of “Lawyer” was fully justified; I don’t mind the money spent.”
3. Tatyana: “For a very long time, my husband and I could not find a high-quality and effective product for our cat. She often travels out of town with us, so the risk of picking up any parasites is always very high. At first they used drops, I don’t know if this is how it’s supposed to be or if it’s some kind of allergic reaction, but they started to cause fur to come out in clumps in the treated areas. Of course, soon everything healed again, but for the first time after treatment the cat looked simply terrible. We decided to try a collar instead; we read a lot of positive reviews about it, but how effective it was became clear when the tick actually bit under it. The veterinarian recommended “Advocate”, although after an unsuccessful experience with other drops I didn’t particularly want to return to a drug of the same type. Fortunately, this time the hair did not come out, and we did not notice any other side effects or allergies. The fact that “Advocate” really works became clear after it helped us get rid of fleas, since then we have been using only this product and hope that its quality will remain at the same level over time.”