When to inject Fosprenil for cats - antiviral: instructions and dosage

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• Veterinary drug

• Drug name: Fosprenil
• Latin name: Phosprenyl
• Pharmacological group - herbal medicine, diuretic herbal extract
• Release form: Bottles of 2, 5, 10, 50, 100 ml. Bottles of 0.45 and 2 l. Liquid dosage form.
• Type of animal: Cats and other types of animals
• Active ingredient: polyprenolic phosphates
• Pharmacodynamics: metabolic, antioxidant, immunostimulant
• Indications: Additional pathogenetic therapy for infections, infestations, internal diseases
• Dose: 1 ml per kg SC, IM, orally or 1/2 dose IV, the dose can be divided into 1-3 administrations per day for 7-14 days.
• Manufacturer. Micro-plus", Moscow (Russia)
• Therapeutic efficacy evidence index: C (D)

Pharmacology

Fosprenil stimulates the main parameters of the cat’s body that regulate body homeostasis:

• Increasing the body's natural resistance
• bactericidal activity of blood serum and phagocytosis
• Strengthening the humoral immune response in cats to vaccines, thereby increasing the body's specific resistance to infections
• Reduces the incidence of disease in kittens
• Activates metabolic processes in cells, tissues and organs
• Has minor antiviral activity against herpesviruses, orthomyxoviruses, paramyxoviruses, togaviruses, feline coronaviruses
• Minor hepatoprotective, cardioprotective, and antioxidant properties have been described

Contraindications and possible side effects

A contraindication for the use of the product is its individual intolerance to animals. When it is detected, Fosprenil is replaced with an analogue that the cat’s body perceives normally.

A contraindication for the use of Fosprenil is individual intolerance to animals.

Acceptable side effects from using the medicine are considered to be a slight increase in body temperature and pulse. Rarely, after the injection, the animal may become drowsy and apathetic. This reaction is also acceptable and does not require treatment. It goes away in a few hours.

Procedure for use and dosage of fosprenil

Fosprenil is prescribed to cats (strictly according to the instructions) to stimulate nonspecific resistance, to prevent and treat viral infections, enhance the immune response to the vaccine, and reduce morbidity. The drug is administered intramuscularly, subcutaneously, intravenously or orally. If necessary, the product can be used to wash the mucous membrane of the eye and nasal cavity in domestic cats.

When treating viral and bacterial infections in kittens, Fosprenil is prescribed for 5-7 days in doses:

• 0.25 kg body weight - single dose 0.075 ml, daily dose - 0.25 ml
• 0.5 kg body weight - single dosage - 0.15 ml, daily dosage - 0.5 ml
• 0.75 kg body weight - single dose 0.225 ml, daily dose - 0.75 ml
• 1 kg of body weight - single dose 0.3 ml, daily dose - 1 ml
• 1.5 kg body weight - single dose 0.45 ml, daily dose - 1.5 ml
• 2 kg body weight - single dose 0.6 ml, daily dose - 2 ml

When treating viral and bacterial infections in cats, Fosprenil is prescribed for 5-7 days in doses:

• 3 kg body weight - single dose 0.6 ml, daily dose - 2.1 ml
• 3.5 kg body weight - single dose 0.7 ml, daily dose - 2.45 ml
• 4 kg body weight - single dose 0.8 ml, daily dose - 2.8 ml
• 4.5 body weight - single dose 0.9 ml, daily dose - 3.15 ml
• 5 kg body weight - single dosage - 1 ml, daily dosage - 3.5 ml
• 6 kg body weight - single dose 1.2 ml, daily dose - 4.2 ml

Fosprenil, in large daily doses, should be administered to cats either at two or three points, or in three to four injections throughout the day, or half the dose intravenously.

Indications for use

The composition is effective against coronavirus, herpesvirus, paramyxovirus, togavirus, and orthomoxovirus.

As a preventive measure, Fosprenil is prescribed to cats that have had contact with a sick animal.

In acute pathologies, the drug is used as an emergency aid, which in a short time allows to stop the progression of the disease.

As a preventive measure, the medicine is prescribed to cats that have had contact with a sick animal.

The main indications for the use of Fosprenil are:

• panleukopenia (distemper);
• rhinotracheitis – if it was caused by an infection;
• calcivirosis;
• infectious lesions of the abdominal cavity with severe manifestations of intoxication;
• viral lesions of the respiratory system;
• food poisoning - the drug is prescribed to relieve inflammation and intoxication.

Before vaccinations, cats may be advised to administer medication to boost the body's immune response. The measure is not always used.

Important! A veterinarian may prescribe a course of Fosprenil if a domestic cat has spent several days outside. The product is needed to prevent the development of the disease if there is a possibility that the animal has been infected with the virus.

Personal prevention measures

According to the instructions, empty drug containers must not be used for household purposes; it must be disposed of with household waste. If the drug accidentally gets on the skin or mucous membranes, it should be washed off immediately with running water and soap. When using Fosprenil, it is necessary to follow the rules of personal hygiene and safety precautions provided for when working with medicinal products for veterinary use. At the end of the work, you should thoroughly wash your face and hands with soap and rinse your mouth with water.

People with hypersensitivity to the components of the drug should avoid direct contact with Fosprenil. All work with the drug should be carried out using special clothing and personal protective equipment (rubber gloves, goggles, respirator or protective mask). While working with the drug, do not drink, smoke or eat. If allergic reactions occur and/or if the drug accidentally enters the human body, you should immediately contact a medical facility (bring with you the instructions for use of the drug or the label).

Composition and release form

The drug is available in the form of a solution intended for injection, which is also used orally. The drug is bottled in transparent glass bottles with a volume of 10 to 100 ml. The medicine is also packaged in ampoules of 2 ml and 5 ml. The solution is colorless, sometimes with a slight yellowish tint.

The active ingredient in the composition is disodium salt of polyprenols phosphate, obtained from pine needles. Additional components of the composition: glycerin, ethyl alcohol, polysorbate 80 and water for injection.

Learn about essential antimicrobials in animals

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Information on the cost of veterinary medicine and its analogues

Fosprenil is available in veterinary pharmacies without a prescription. On average, the cost of packaging 5 bottles of them, with a capacity of 10 milliliters each, is 850 rubles.

You can buy Fosprenil at any veterinary pharmacy without a doctor's prescription.

Among Fosprenil analogues one can see many veterinary drugs with immunomodulating properties. We are talking about Gamavit, Maksidin, Forvet and others.

The main role of the immune system is to maintain homeostasis by recognizing foreign antigens. Violations of its functions can be corrected with the help of immunotropic drugs, including immunomodulators. Immunomodulators are most widely used to treat dogs and cats. In livestock farming, immunomodulators are used for therapeutic and prophylactic purposes to increase natural resistance, stimulate the growth and development of young animals, in pathological conditions accompanied by a decrease in immunoreactivity, including viral and bacterial diseases, to normalize the blood count, prevent and correct stress and its consequences, for detoxification, etc.

Among herbal preparations, Fosprenil (sodium polyprenyl phosphate, from Siberian fir needles), which has immunomodulatory, antiviral, anti-inflammatory, adjuvant and other pharmacological activities, is widely used in animal husbandry.

V. Lavrenova, marketer at the publishing house "Agricultural Technologies"

https://www.tsenovik.ru/articles/veterinariya/immunobiologicheskie-preparaty-dlya-produktivnykh-zhivotnykh/

Table: list of drugs analogues of Fosprenil

Veterinary medicine	Manufacturer information	Components	Who is it shown to?	List of contraindications	Information about the release form	Price
Gamavit	(Russia Moscow)	The active ingredients are presented in the form of denatured emulsified placenta and sodium nucleinate in saline solution, which contains amino acids and vitamins.	Prescribed to stimulate growth and development, for the preventive purpose of anemia, rickets and other ailments. Prescribed for stressful situations, exhaustion, dermatitis, hypovitaminosis, toxicosis in pregnant individuals	Hypersensitivity to the ingredients of the drug	Injection solution in a glass bottle of 6, 10 and 100 ml	From 150 rub. for 10 ml
Maxidin	(Russia Moscow)	The main component is germanium bis (pyridine-2,6-dicarboxylate) 1.5 mg or 4 mg. Excipients include: water for injection; sodium chloride; monoethanolamine	For therapy: rhinitis; conjunctivitis; keratoconjunctivitis	Intolerance to the components of the medication	Eye and intranasal drops in 5 ml containers. Injection solution in a 5 ml bottle (5 pcs. in a pack)	From 60 rub. for a bottle of eye drops
Forvet	(Russia, Sergiev Posad)	The active ingredient is panavira. Auxiliary: sodium chloride and injection water	Prescribed in the complex treatment of infectious diseases of the conjunctiva and cornea	Hypersensitivity to the constituent ingredients of the veterinary drug	Injection solution in ampoules of 5 ml or bottles of 5, 10, 20, 50 and 100 ml. Eye drops 10 ml	From 370 rub. per pack (3 bottles)

Photo gallery: Fosprenil analogues

The most popular immunostimulating veterinary drug is Gamavit

Forvet is used in the complex treatment of infectious diseases of the conjunctiva and cornea

Maxidin is used for the treatment of rhinitis, conjunctivitis in cats

Properties

Fosprenil has a broad spectrum of antiviral action both in vitro and in vivo; increases the body's resistance to diseases caused by parvoviruses, caliciviruses, herpesviruses, paramyxoviruses, as well as a number of other animal viruses.

The drug modulates, within physiological limits, the functioning of the natural resistance system, has anti-inflammatory activity, enhances the immune response to vaccines, is a hepatoprotector and detoxicant, and stimulates the growth and development of animals.

How to give

Fosprinil can be administered to dogs:

• by ingestion (orally);
• by instillation (for example, for a runny nose, into the nose);
• intramuscular and intravenous injections.

A veterinarian must prescribe a treatment regimen for your dog.

To administer Fosprenil orally, you need to pull back part of your pet's lip and slowly pour the drug into the cheek. In this case, either a special introducer syringe or a disposable syringe without a needle is used. When taken orally, the single dose of Fosprenil is doubled.

If it is necessary to apply Fosprenil to the dog's eyes or nose, use a pipette washed in warm water. Fosprenil is diluted 3 times with saline and pipetted.

Then you need to pull back the lower eyelid with one hand and press the pipette cap with the other. It is necessary to bury it closer to the inner corner of the eye. Excess medication that comes out of the eye is wiped with a cotton swab or napkin.

An intramuscular injection (into the thigh or shoulder muscle) is given with a sterile syringe selected depending on the size of the dog and the dosage of the medication.

When carrying out medical procedures using Fosprenil, it is necessary to use:

1. medical gloves;
2. protective glasses;
3. respirator (mask).

Attention! To prevent infection, do not touch the syringe needle with your hands, and do not touch anything other than the dog’s skin with the needle!

How to give an injection?

Fosprenil must be warmed in your hands to 37 degrees and the syringe filled with the required dosage, making sure that no air gets into it.

You need to start administering the injection after making sure that the injection site is not inflamed or damaged and that the dog is relaxed. If the muscles are tense, you need to first calm the pet, for example, by massaging it. Skin treatment before injection is not required, since dogs are protected from the penetration of bacteria inside by a dense skin layer.

The injection for dogs up to 10 kg is made at a depth of 1-1.5 cm. For larger pets, the needle insertion depth increases to 3.5 cm. The syringe is positioned perpendicularly to better achieve the goal.

Important! When changing the needle, it is necessary to remove air from it. To do this, you need to press the piston before a drop appears from the needle hole.

The appearance of a small amount of blood after injecting a dog does not pose a threat. A 20-minute cold compress will help stop heavy bleeding. As a last resort, if the compress does not help, you should contact your veterinarian to prescribe hemostatic drugs.

Analogues of the drug

The list of immunomodulatory and antiviral drugs for cats with an effect identical to Fosprenil includes several drugs. Their composition and active substances differ, but the main effect is similar:

1. Gamavit. It is produced on the basis of animal placenta and is a dietary supplement containing amino acids, vitamins and mineral components. Dietary supplements are available in the form of sterile injection solutions or preparations for oral administration.
2. Maxidin. The formula is based on organogermanium compounds and is a powerful immunomodulator in the form of an injection solution or eye drops.
3. Forvet. It is an active complex based on mono- and polysaccharides from plant materials. There are 2 forms of the medicine: injection solution and eye drops.

Fosprenil is a universal antiviral and immunomodulatory drug that is widely used by veterinarians and pet owners as a therapeutic and prophylactic agent. When treating cats, the medication does not cause adverse reactions and demonstrates high effectiveness.

Reviews about the treatment

Kirill, veterinarian: “Fosprenil is an effective and proven drug for combating viral diseases. Thanks to its safe composition, it has virtually no contraindications and is suitable for different breeds of cats. There are no significant disadvantages or side effects.”

Svetlana, Arkhangelsk: “In my city, Fosprenil is not a common drug, which is a pity. I give my cat medicine not only to fight viral diseases, but also as a preventive measure. We managed to cure 7 kittens with herpes virus.”

AGREED Deputy Head of Rosselkhoznadzor ________________________ ________________________ ________________________

INSTRUCTIONS

on the use of Fosprenil to stimulate nonspecific resistance

and treatment of viral infections in animals and birds

(developer organization: Micro-plus CJSC, 123098 Moscow, Gamaleyi St., 18)

1. General information

1. Trade name of the drug: Phosprenyl.

International nonproprietary name: disodium salt of polyprenols phosphate.

2. Dosage form: solution for injection.

Fosprenil contains 4 mg of disodium salt of polyprenols phosphate in 1 ml as an active substance, and glycerin, ethanol, Tween-80 and water for injection as excipients.

3. In appearance, the drug is a transparent or slightly opalescent solution, colorless or with a yellowish tint.

The shelf life of the medicinal product, subject to storage conditions, is 2 years from the date of production. After opening the initial packaging, the drug cannot be stored.

Do not use Fosprenil after the expiration date.

4. Fosprenil is produced packaged in 10 ml and 50 ml glass bottles of appropriate capacity, sealed with rubber stoppers reinforced with aluminum caps.

Vials with the drug are placed in cardboard packs. Each unit of packaging is supplied with instructions for use.

5. Fosprenil should be stored in the manufacturer’s sealed packaging, separate from food and feed, in a dry place, protected from direct sunlight, at a temperature of 4°C to 25°C.

6. The drug should be stored out of the reach of children.

7. Unused medicinal product is disposed of in accordance with legal requirements.

8. Dispensing conditions: without a veterinarian's prescription.

II Pharmacological properties

9. Fosprenil is an antiviral drug with immunomodulatory properties.

10. Disodium salt of polyprenols phosphate, which is part of the drug, activates natural resistance systems (bactericidal activity of blood serum and phagocytosis), enhances the humoral immune response to vaccines, thereby increasing the body's resistance to infections and reducing morbidity. Disodium phosphate salt of polyprenols activates metabolic processes in cells and, accordingly, increases weight gain while reducing feed costs. Disodium phosphate salt of polyprenols has antiviral activity against paramyxoviruses, orthomyxoviruses, togaviruses, herpesviruses, coronaviruses and some other viruses. After parenteral administration, disodium salt of polyprenols phosphate enters the animal’s bloodstream, accumulates mainly in the tissues of the liver, spleen and reproductive organs, reaching maximum concentrations after 0.5-3 hours and remains at a therapeutic level for 10-16 hours. It is excreted from the body mainly in feces and urine.

In terms of the degree of impact on the body, Fosprenil is classified as a low-hazard substance (hazard class 4 according to GOST 12.1.007-76); in recommended doses it does not have a locally irritating, allergenic, embryotoxic, teratogenic or carcinogenic effect.

III. Application procedure

11. Fosprenil is used in agricultural animals, domestic animals, fur-bearing animals and poultry to stimulate nonspecific resistance, for the prevention and treatment of viral infections, enhancing the immune response to vaccine administration, reducing morbidity and increasing weight gain in animals and poultry.

12. A contraindication to the use of the drug is the increased individual sensitivity of animals and birds to the components of Fosprenil.

13. The drug can be used in various ways: intramuscularly, subcutaneously, intravenously (in horses and productive animals) or orally.

Treatment with Fosprenil should be started as early as possible after the onset of clinical signs of the disease. Therapy is most effective in the prodromal period. For viral infections, it is necessary to combine Fosprenil with symptomatic and pathogenetic therapy, especially in severe and complicated forms of infections. In severe cases of the disease, it is recommended to double the therapeutic dose of Fosprenil. Treatment is stopped 2-3 days after the main symptoms of the disease disappear. If necessary, repeated courses of treatment may be prescribed.

When treating viral infections of small domestic animals, Fosprenil is prescribed for 5-7 days in the doses (ml/kg) indicated in Table 1.

Table 1

Animal species	Puppies	Dogs	Kittens	Cats
Single dose	0,3	0,2	0,3	0,2
Daily dose	0,9-1,2	0,6-0,8	0,9-1,2	0,6-0,8

With a large daily dose, Fosprenil should be administered either at two or three points, or in three to four injections during the day.

For canine distemper in dogs, in order to avoid relapses, the drug should be administered for at least 14 days, even if the clinical signs of the disease disappear. The duration of the course, if necessary, can be increased to 1 month.

For the purpose of nonspecific prevention of diseases and reduction of mortality, Fosprenil is administered at a dose of 0.05 ml/kg body weight according to the schedule indicated in Table 2.

table 2

Kind of animal	Infections	Method of administration	Number of injections
			Days after starting prophylaxis:
			1	2	3	5	10	15
Pigs	Intestinal	in/muscularly, orally	1			1	1
Chickens	Respiratory	aerosol*	1	1	1	1	1	1
	Intestinal	orally	1			1	1
Horses	Respiratory	IV	1	1	1	1	1	1
	Intestinal	IV	1			1	1
Minks	Secondary infections in Aleutian disease	orally	Once every 5-7 days during the entire production cycle

* - to prepare a working solution, 20 ml of Fosprenil is diluted in 1 liter of water with 10% glycerin and sprayed using aerosol generators such as SAG or APA at the rate of 0.4 ml of working solution per 1 m3 of poultry room with an exposure of 15 minutes.

To reduce morbidity, mortality, increase weight gain, reduce feed costs for young animals (pigs, horses, cattle) and poultry (chickens) in the first month of life, Fosprenil is administered in a prophylactic dose of 0.05 ml/kg intramuscularly, orally or in birds with water on the 2nd, 5th, 10th, 14th and 20th days of life. Fosprenil is given to fur-bearing animals with food once every 7 days during the 1st month after weaning, then once every 14 days before slaughter.

In order to increase the immune response to vaccines and prevent post-vaccination complications, Fosprenil at a dose of 0.05 ml/kg is administered simultaneously with the vaccine in different syringes intramuscularly, orally or in birds with water. The drug is not used for revaccination.

14. There have been no cases of overdose, side effects or complications with the use of Fosprenil.

15. No specific effects were identified during the first use of the drug and upon its discontinuation.

16. Fosprenil can be used in pregnant animals, in animals during lactation and in the offspring of animals and birds.

17. Omissions should be avoided when administering the next dose of Fosprenil, as this may lead to a decrease in the therapeutic effectiveness of the drug. If you miss one dose, give it as soon as possible. Further, the interval until the next administration of the drug does not change.

18. When using Fosprenil in accordance with these instructions, side effects and complications, as a rule, are not observed.

If allergic reactions occur, stop using the drug and prescribe antihistamines or other symptomatic treatment.

19. The drug is not recommended for use with steroid drugs due to a decrease in the therapeutic effect of Fosprenil. It is not recommended to dilute Fosprenil with saline solutions.

20. Products from animals and birds that have been treated with Fosprenil are used for food purposes without restrictions.

IV. Personal prevention measures

21. When using the drug, it is necessary to follow the rules of personal hygiene and safety precautions provided for when working with medicinal products for veterinary use.

22. All work with Fosprenil should be carried out using special clothing and personal protective equipment (rubber gloves, goggles, respirator or protective mask). While working with the drug, do not drink, smoke or eat. At the end of the work, you should thoroughly wash your face and hands with soap and rinse your mouth with water.

Empty medicinal product containers must not be used for household purposes; it must be disposed of with household waste.

23. People with hypersensitivity to the components of the drug should avoid direct contact with Fosprenil. If the drug accidentally gets on the skin or mucous membranes, it should be washed off immediately with running water and soap. If allergic reactions occur and/or if the drug accidentally enters the human body, you should immediately contact a medical facility (bring with you the instructions for use of the drug or the label).

Advantages and disadvantages of the drug

The advantages of Fosprenil include several factors:

• accessibility (the medicine can be bought at almost any veterinary pharmacy);
• low price (from 140 rubles per 10 ml bottle);
• no contraindications (except allergies);
• low risk of side effects;
• Fosprenil does not contain toxic substances.

The disadvantage of this immunomodulator is its unproven effectiveness (or its low degree). There is currently no scientific evidence that the drug actually affects the course of treatment, for example, for viral infections. All conclusions about the drug are made only on the basis of the experience and practice of those people who used it. In addition, Fosprenil is most often used in combination with other medications, so even successful treatment may be due to them.

After talking with the seller from the nearest veterinary pharmacy, I came to the conclusion that Fosprenil may also have counterfeits. Of course, the pharmacist didn't tell me how to identify them. Only one thing is clear: you need to carefully study the packaging, and it is better to buy 10 ml bottles immediately in a box, and not individually. By the way, if the veterinary pharmacy did not offer you several different packaging options at once, then there is a great chance of buying real Fosprenil.

One of the disadvantages of Fosprenil is the likelihood of “running into” a fake

Side effects

Being a low-toxic drug, Fosprenil practically does not cause unwanted reactions and health problems.

According to GOST, the medicine belongs to hazard category 4 and has no mutagenic, carcinogenic, embryotoxic or teratogenic effects. After injections, there is no irritation of the skin, and the medication itself does not have allergenic properties.

During course therapy in individual cases, an allergic reaction may occur in cats. Having noticed the first manifestations of intolerance, you should stop injections, use an antihistamine and contact a veterinary clinic for help.

Allergy symptoms include high body temperature, rapid heartbeat, drowsiness and apathy.

Storage conditions

Store Fosprenil in a dark place at a temperature of 4-6 degrees Celsius, away from children and food. It is recommended to place the bottle in a box.

The shelf life of the drug if stored correctly is 2 years (or 24 months). After the expiration date, the medicine must be disposed of and not used under any circumstances!

Average cost in Russia

In recent years, trust in domestic drugs among pet owners has increased significantly.
This is especially true for products produced on the basis of natural ingredients and containing plant substances. Fosprinil, which contains extracted extracts of fir, spruce, cedar and pine, has a high level of biological activity, remaining the most inexpensive and at the same time effective drug

.

The average retail price for Fosprenil for dogs in Russia is:

• The cost of a 10 ml bottle is 140 rubles.
• The cost of a 50 ml bottle is 620 rubles.

Fosprenil for cats: reviews

In most cases, this solution has positive reviews. Pet breeders have noted a rapid improvement in the cat’s condition even with severe illnesses (for example, with the herpes virus, improvement occurs approximately on the third day of complex therapy).

In addition, buyers note that most pets easily tolerate treatment with the drug, since the injections are practically painless, and the possibility of oral administration makes the medication extremely convenient for treating kittens and severely weakened animals.

Another advantage noted by owners of domestic cats is the attractive cost of Fosprenil. A simple injection solution is much cheaper than expensive antiviral drugs in tablets.

Negative reviews are extremely rare; they mainly contain information about side effects in the form of lethargy and fever, but these phenomena are mainly associated with incorrect dosage calculations.

Interaction of Fosprenil with other drugs

Veterinary practice and the manufacturer’s recommendations for the use of Fosprenil allow us to draw a number of conclusions. Many drugs are quite compatible with this immunomodulator. But even if the instructions for use of another medicine do not indicate that it cannot be combined with Fosprenil, when treating at home, it is better to consult a veterinarian. Sometimes veterinarians give advice based on their experience.

Kids and cats receive a bunch of other drugs, antibiotics, Roncoleukin, Gamavit, dripped into their eyes and nose. The mouth is treated with Dentavegin. The kittens are less active than usual, they sleep a lot, but they eat and even try to play.

Klepa, forum user

https://mauforum.ru/viewtopic.php?p=757437

If Fosprenil is used for a better response to vaccination and prevention of complications after it, then the immunomodulator is administered along with the vaccine (dosage - 0.05 ml per 1 kg of cat's body weight). You just can’t mix these solutions - the drugs must be administered in different syringes (into the muscle or orally). Important: when re-vaccinating cats, Fosprenil is not used.

It is not recommended to combine this remedy with steroid drugs (they reduce the therapeutic effect of the immunomodulator). In addition, veterinarians do not recommend diluting Fosprenil with saline or other liquids.

Fosprenil is often combined with other drugs

Contraindications and side effects

You can be allergic to any drug. Depends on individual tolerance.

Lara, forum user

https://www.rat.ru/forum/index.php?topic=31114.0

There is only one contraindication to the use of Fosprenil - individual intolerance to the components of the drug. Accordingly, a side effect of use is an allergy to any component of the drug. In this case, stop using Fosprenil. To get rid of allergy symptoms, the use of an antihistamine (for example, Diazolin) or another symptomatic drug may be prescribed.

By the end of the second day there were no results from the treatment, so fosprenil 0.2 s.c. was added. After about 4 hours, we noticed that the kitten began to breathe more often, they sat him down, breathing, rocking. They gave me cardamine, aminophylline and dexamethasone. No reaction. They took diphenhydramine in case of an allergic reaction from fosprenil and the kitten came back to life.

Polina1234, forum newcomer

https://www.bkvet.ru/forum/showthread.php?t=2597